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Natural Killer (NK) Cell and Natural Killer T-Cell Panel

Ordering Tests

Test Name (Aliases)

Natural Killer (NK) Cell and Natural Killer T-Cell Panel

Test Code

LAB1779 Miscellaneous Test

Code Alt

2013805

Tests Included

NK and NKT cell subsets;Natural killer (NK) cells are identified by the absence of CD3 and the expression of CD16 and/or CD56.

Method

Semi-Quantitative Flow Cytometry

Performing Lab

ARUP

Days Performed

Reported in 1 – 3 days of receipt

Required Forms

Required Forms

Requirements Preps

Requirements Preps
Specimen Collecting and Handling

Specimen Type

EDTA Whole Blood

Collection Container

Lavender EDTA tube

Required Volume

4 mL (min: 1 mL)

Specimen Handling

4 mL (min: 1 mL)

Name on Report

Name on Report

Clinical Use

Natural killer (NK) cells are identified by the absence of CD3 and the expression of CD16 and/or CD56. NK cells are divided according to the expression of CD16 and CD56 into cytotoxic NK cells (CD3-CD16+CD56dim) that represents approximately 90 percent of NK cells, and cytokine-secreting or regulatory NK cells (CD3-CD16-CD56bright) that represents approximately 10 percent of NK cells. NK cells act against virally-infected cells and tumor cells and may be increased or decreased in various immunologic abnormalities. NK cells also have a role in the adaptive immune response through cytokine production. NK-like T-cells have properties of both T-cells and NK-cells, expressing both CD3 and NK-associated antigens.

The cytotoxic NK cells (CD3-CD16+CD56dim) and cytokine-secreting or regulatory NK cells (CD3-CD16-CD56bright) are reported as a percentage of the total NK cells. All other populations are reported as a percentage of the total lymphocytes.


Reference Range

Reference Range

Critical Values

Critical Values
Charge and Set-up

Coding CPT

86356 x 3; 86357; 86359

Coding Loinic

Coding Loinic

Additional Information

Review our policy provided here to learn more about Riverview Health Laboratory’s services, requirements for orders and specimen submission.

Lab Client Services Guidelines

Lab Collection for Nursing Home and Assisted Living

Modified Sample Collection for Long-Term Care Clients – COVID-19 Plan

The Laboratory evaluates quality and integrity for each specimen submitted for testing in order to ensure accurate results. The policy for evaluation and handling of samples that do not meet quality criteria is viewable here.

Specimen Acceptability and Rejection Policy

Lab Client Portal

Riverview Health Laboratory can now connect with outreach clients to provide electronic order entry and results using the LabWorks Portal. Access to the portal is available for professional clients in the clinic, skilled care, and assisted living location. To request site access for your health care team, please contact the Laboratory at 317.776.7241.
Riverview LabWorks Portal

Lab Client Portal

The following forms may be used to submit requests for laboratory services.

Cytopathology Requisition Form

Surgical Pathology and Medical Cytology Requisition Form

Lead Form – Minors Only

AFP Maternal – Prenatal Quad Form

Patient Collection Instructions

Collection Instructions – Clean Catch Mid Stream Urine

Collection Instructions – 24-Hour Urine

Collection Instructions – Pinworm Prep

Collection Instructions – Semen Fertility

Collection Instructions – Semen Post Vasectomy

For More Information

Riverview Health Laboratory
395 Westfield Road
Noblesville, IN 46060

 

317.776.7241